Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Displaying 1 - 4 of 4

Electroactive Supramolecular Systems for Informed Electrochemical Sensor Development

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Quintero Arias, Carlos, Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Keske, Eric, Degree committee member (dgc): Thompson, Karen, Degree granting institution (dgg): Trent University
Abstract: <p>In an effort to improve upon existing analytical methods, electrochemical sensors offer portable, cost-effective alternatives to traditional lab-based techniques. Recent advances in supramolecular chemistry offer a unique alternative to achieve high selectivity while also benefitting from facile scaling for mass production. Thus, by incorporating host-guest chemistry with electrochemical… more

Environmental Remediation Applications of Chemically Activated Tropical Hardwood Waste

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): France, Hamant Edward, Thesis advisor (ths): Vreugdenhil, Andrew J, Degree committee member (dgc): Martic, Sanela, Degree committee member (dgc): Narine, Suresh, Degree granting institution (dgg): Trent University
Abstract: <p>Innovative strategies to manage copious waste streams by upcycling feedstocks to valorized products which are then used in environmental remediation applications is an attractive circular economy model. This thesis explores this approach using waste wood generated from the milling of Chlorocardium rodiei (greenheart), a tropical hardwood species abundant in Guyana. We evaluate the… more

Effect of mfsd8 deletion on the secretome and transcriptome of Dictyostelium discoideum

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Gray, Joshua, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Saville, Barry, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
Abstract: <p>Mutations in the CLN7 (MFSD8) gene, causes CLN7 disease, a subtype of neuronal ceroid lipofuscinosis. MFSD8 is a lysosomal transmembrane protein that transports chloride across membranes. Experimentation regarding Dictyostelium discoideum revealed that mfsd8 deficiency altered lysosomal enzyme activity. During starvation, the aggregation of mfsd8¬¬- cells was delayed, and cells formed… more

Investigation of the Oxidative Activity of Giardia Flavohemoglobins

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Decorso, Isabelle, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
Abstract: <p>Flavohemoglobins are enzymes primarily implicated in nitrosative stress due to their high nitric oxide (NO) dioxygenase activity and transcriptional upregulation in response to NO. Giardia intestinalis assemblages A, B, and E possess flavohemoglobins (gFlHb) that may function beyond their NO dioxygenase activity, potentially contributing to oxidative stress regulation, as transcriptional… more