Trent University Graduate Thesis Collection

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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    Investigation of the Oxidative Activity of Giardia Flavohemoglobins

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Decorso, Isabelle, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
    Abstract: <p>Flavohemoglobins are enzymes primarily implicated in nitrosative stress due to their high nitric oxide (NO) dioxygenase activity and transcriptional upregulation in response to NO. Giardia intestinalis assemblages A, B, and E possess flavohemoglobins (gFlHb) that may function beyond their NO dioxygenase activity, potentially contributing to oxidative stress regulation, as transcriptional… more