- Collections Home
- Alumni House Collection
- Arthur Virtual Archive
- Faculty Research Collection
- Journal GenObs
- Margaret Laurence Collection
- Stories of Resistance, Resurgence, and Resilience in Nogojiwanong / Peterborough
- Trent Community Research Centre Project Collection
- Trent University Academic Calendar Collection
- Trent University Archives
- Trent University Graduate Thesis Collection
- University Heritage Collection
Graduate Theses & Dissertations
-
- Influence of nitrogen and sulfur on cadmium tolerance in Euglena gracilis
- Heavy metal pollution threatens human and ecosystem health. E. gracilis was investigated for its potential use in bioremediation due to its tolerance for heavy metals and ability to sequester them from the environment. E. gracilis can remove metals by producing metal binding compounds enriched in sulfur and nitrogen. In this thesis, E. gracilis cultures that were pretreated with elevated levels of sulfur or nitrogen had increased tolerance to CdCl2 compared to non-pretreated cultures. RNA-sequencing revealed that both pretreatments led to transcript level changes and that exposure to CdCl2 led to further transcript level changes. Gene ontology (GO) enrichment analysis reflected changes in nitrogen and sulfur metabolism as well as physiological processes related to metal binding. The data from this thesis revealed important transcription level changes that occur when E. gracilis is challenged with CdCl2 and helps us understand how organisms adapt to heavy metal pollution in the environment. Author Keywords: bioremediation, Cadmium, Euglena gracilis, GO-enrichment, metal-binding, RNA-Sequencing
Search Our Digital Collections
Sort Results
Filter Results
Date
Collection
Author Name
- Kennedy , Victoria (1) + -
Degree
- Master of Science (1) + -
Degree Discipline
Subject (Topic)
- Environmental science (1) + -